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Join us at Brenus Pharma
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About Brenus
Based in Lyon with a team of 25 people, Brenus Pharma is a French clinical-stage biotech company developing next-generation in vivo immunotherapies targeting solid tumors, which are responsible for most therapeutic failures in oncology. Our mission is to provide an effective treatment option for patients who have no alternative to chemotherapy.
Our approach
Our proprietary technology is designed to mimic cancer biology and educate the patient’s immune system to recognize and eliminate malignant cells. Our lead candidate, STC‑1010, targets microsatellite‑stable (MSS) colorectal cancer, a form that responds poorly to current immunotherapies, and entered a Phase I/IIa clinical trial in 2025. We are supported by leading worldwide investors and public stakeholders (Bpifrance, France2030, etc.).
Brenus aims to become a key player in immuno‑oncology by combining breakthrough innovation with tangible impact for patients.
The job
About the role
We are looking for an immuno-oncology scientist with strong biological expertise and the ability to analyze and interpret complex molecular data. The position is computational and does not include routine laboratory work.
The R&D Project Manager will support Brenus Pharma’s preclinical and translational/innovation research programs by analyzing and interpreting biological data. The successful candidate will work at the interface between immunology, oncology and bioinformatics. This positionis intended for a scientist with a strong understanding of cancer immunology who is also comfortable working with sequencing and multi-omics data
Missions
Scientific data analysis
- Analyze and interpret data generated from preclinical and translational studies
- Integrate molecular and functional data to investigate MoA, immune signatures and biomarkers
- Contribute to the analysis of transcriptomic, genomic and immunological data and turn the findings into clear scientific conclusions
Support to R&D programs
- Contribute to the definition of scientific questions, study designs and analysis strategies
- Propose relevant complementary analyses based on emerging results and program needs
Scientific collaboration and communication
- Work with internal teams, academic collaborators and external service providers to review data and support scientific interpretation
- Prepare clear reports, figures, presentations and materials for scientific communications
What you bring
Education
- PhD in immunology, immuno-oncology, computational biology, or related discipline
Key skills
- Strong knowledge of tumor immunology and cancer biology
- 3–5 years of relevant experience in immuno-oncology or translational science, including experience gained during the PhD
- Previous experience working in or collaborating with a cancer center, or contributing to clinical research, would be an advantage
- Hands-on experience in biological data analysis and the ability to interpret complex results in their scientific context
- Scientific rigor, autonomy, good collaboration and communication skills, and professional proficiency in English
Technical skills
- Good understanding of statistical analysis and experience using GraphPad Prism.
- Hands-on experience in bulk RNA-seq analysis, from raw data to biological interpretation.
- Experience in at least one complementary field such as WES, TCR-seq or immunopeptidomics.
About the position
- Type of contract: Full-time, 24-month CDD, with the possibility oftransitioning to CDI
- Department: R&D-Innovation
- Location : Lyon, France, with the possibility of remote working
- Start : As soon as possible
For any information : careers@brenus-pharma.com
Culture and values
By joining the team, you become part of a company where science, people and purpose move forward together. At Brenus, our culture is built on curiosity, learning, and the desire to grow,both individually and collectively. We value creativity, open‑mindedness, teamwork, and the joy of sharing ideas, challenges, and new experiences. Collaboration, mutual support, and finding solutions together are at the heart of how we work every day. Beyond our projects, we aim to have a positive impact in healthcare: advancing scientific innovation by improving patients’ lives.
Ready to make an impact?
